DALLAS: New research by Rockefeller University scientists and their colleagues have identified a series of naturally occurring molecular steps – known as a pathway – that can dampen the production of amyloid-β. These results suggest a new route in the search for Alzheimer’s therapies.
“Our discovery centres on a protein called WAVE1, which we found to be important in the production of amyloid-β. The reduction of WAVE1 appears to have a protective effect against the disease,” says the study author.
“By targeting steps within this newly discovered pathway,” he adds, “it may be possible to develop drugs to reduce amyloid-β that potentially could be used to either treat or prevent Alzheimer’s disease”…