LOS ANGELES: Although there are many potential predictors of conversion from mild cognitive impairment (MCI) to dementia, several may be modifiable, new research suggests.
A meta-analysis of 62 studies showed that diabetes and prediabetes increased risk for conversion from MCI to Alzheimer’s dementia and all-cause dementia. In addition, metabolic syndrome, low dietary folate, the presence of any neuropsychiatric symptoms, and having depressive symptoms all predicted dementia conversion in patients with various forms of MCI, whereas consumption of a Mediterranean diet decreased risk.
The factors deemed “potentially modifiable” included diabetes, metabolic syndrome, diet, and neuropsychiatric symptoms…