PHOENIX: A new discovery in Alzheimer’s research could prove to be integral in slowing the cognitive decline that makes the disease so difficult to manage. Researchers have discovered that a certain protein called GPR3 may hold the key to reducing amyloid plaque build-up in the brain.
Researchers believe that the accumulation of proteins in the brain – specifically amyloid plaques – play a major role in the development of Alzheimer’s disease. Over time, proteins in the brain are segmented into different parts – one type of segment is called an amyloid- β peptide.
When amyloid-β peptides build up, they become amyloid plaques, which can block the pathways between nerves and the brain. Eventually, this forces many of the brain’s networks to shut down, which compromises healthy mental function. This causes dementia to develop, which is a hallmark of Alzheimer’s disease.