HOUSTON: Elongated fibres (fibrils) of the beta-amyloid protein form the typical senile plaques present in the brains of patients with Alzheimer’s disease.
A European research team and a team from the United States (Massachusetts Institute of Technology in cooperation with Lund University) have simultaneously succeeded in elucidating the structure of the most disease-relevant beta-amyloid peptide 1-42 fibrils at atomic resolution. This simplifies the targeted search for drugs to treat Alzheimer’s dementia.