DALLAS: A team has studied the aggregation of two of the most common variants of Abeta, namely Abeta 40 and Abeta 42, with 40 and 42 amino acids, respectively, the latter being the variant most closely associated with Alzheimer’s disease. The literature reports that while Abeta 40 self-aggregates to sequentially form dimers (two units), trimers (three units) and tetramers (four units), Abeta 42 self-aggregates to form pentamers (five units) and hexamers (six units). These findings have been cited more than 1000 times and consequently numerous studies have been based on this premise. However, researchers have observed that Abeta 40 and Abeta 42 goes through exactly the same aggregation states.