Researchers find out reason why PPIs linked with dementia

research NEW YORK: Earlier studies had claimed that regular and long-term use of proton pump inhibitors (PPIs) could increase the risks of dementia, cardiovascular disease and renal failure. However, the reason why it was so discovered was recently published in a study.

It is estimated that one in 14 uses an over-the-counter PPI like omeprazole, sold as Prilosec, to treat gastroesophageal reflux disease (GERD) that are also called heartburn or acid reflux. The researchers involved in the study suggested that vascular cells get exposed in vitro to PPIs and this lead to accumulation of cellular garbage in cellular linings. This process accelerates blood vessel aging….

Full story covered in the Dementia Business Weekly.