Research shows estradiol does not affect cognition post-menopause

woman cooling herselfNEW YORK: Hormone replacement therapy in the form of estradiol did not affect memory, global cognition or executive function, regardless of the treatment’s timing in randomised trial.

A new study has thrown into doubt the popular belief that a woman’s memory can be affected by the timing of her menopause and when menopausal hormone replacement therapy (HRT) is started — known as the “timing hypothesis”.

Led by Victor Henderson, professor of neurology and neurological sciences at Stanford University’s school of medicine in California, researchers randomised 567 healthy post-menopausal women, aged 41–84 years, to receive a daily 1mg dose of 17b-estradiol or placebo…

Full story covered in the Dementia Business Weekly.