ALBUQUERQUE: New research examines genetic modifications associated with the development of PD and PD-associated dementia, bringing new investigative tools to bear.
The research uses RNA sequencing to illuminate two phenomena linked with the onset of Parkinson’s disease, differential gene expression and alternative splicing of genes.
The study tracks specific gene alterations implicated in the development of Parkinson’s, noting that gene expression and alternative splicing offer complementary information critical to a full understanding of disease progression. The findings deepen the scientific understanding of the disease, while suggesting new avenues for more comprehensive diagnosis.