NEW YORK: Decreasing aggregates of amyloid beta peptide (Aβ) is the most common strategy for treating Alzheimer’s disease. One treatment that is undergoing phase 3 clinical trials is beta site amyloid precursor protein cleaving enzyme 1 (BACE1) inhibitors, which are predicted to decrease the production of Aβ and prevent neurotoxic fibril and plaque formation. A research group is studying BACE1 inhibitors in mice to further understand how this treatment works…